BONE STRENGTH AND ITS DETERMINANTS IN PERI- AND POSTMENOPAUSAL WOMEN

  • Farida Hafeez Department of Physiology, CMH Lahore Medical College
  • Madiha Ahmad Department of Physiology, CMH Lahore Medical College
  • Shahid Hasan Department of Physiology, CMH Lahore Medical College
  • Rukhshan Kurshid Department of Biochemistry, Fatima Jinnah Medical College, Lahore, Pakistan
Keywords: Osteoporosis, perimenopausal, postmenopausal, bone mineral density, body mass index, oestrogen

Abstract

Background: Diminished bone strength increases the frequency of osteoporosis and fragility fractures. Weight and gonadal status are important determinants of bone mass in women. This study tried to find out the bone strength and its determinants in peri- and postmenopausal age groups of women. Methods: One hundred and twenty females with age range 25–66 years were included in the study. According to their age and menstrual status they were divided into premenopausal (30) perimenopausal (50) and postmenopausal (40). Body Mass Index (MBI) and bone related blood parameter, serum calcium, magnesium, inorganic phosphorus, alkaline phosphatase and estradiol were estimated. Bone mineral density was taken by peripheral densitometer. Results:  Blood chemical parameters were not significantly different in these groups.  The p-value of serum estradiol was highly significant in peri- and postmenopausal groups. BMI was significantly high in postmenopausal as compared to pre and perimenopausal groups. Conclusion: Early menopause, low levels of oestrogen and BMI values can all affect the health of bones in elderly women.

Downloads

Download data is not yet available.
Published
2011-06-30
How to Cite
1.
Hafeez F, Ahmad M, Hasan S, Kurshid R. BONE STRENGTH AND ITS DETERMINANTS IN PERI- AND POSTMENOPAUSAL WOMEN. PJP [Internet]. 30Jun.2011 [cited 27Jul.2021];7(1):37-9. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/787