EFFECTS OF PROLONGED ADMINISTRATION OF LARGE DOSES OF ACTH ON BUFO MELANOSTICTUS TADPOLES

Authors

  • Mahmood Ahmed Department of Physiology, University of Karachi.
  • Ruqaiya Hasan Department of Physiology, University of Karachi, Karachi Pakistan
  • Mansoor Ahmad New York Medical College Valhalla, N.Y U.S.A.

DOI:

https://doi.org/10.69656/pjp.v1i1-2.576

Keywords:

Tadpole, ACTH, Growth

Abstract

The present study reports the effects of different ACTH preparations, in similar and different concentrations on Bofo Melanostictus Tadpoles. Results: ACTH administration proved antagonistic to tadpole growth hormone. There seemed to be no dose-effect response when ACTH was administered in 0.02 IU/ml instead of 0.01 IU/ml. Similar ACTH concentrations with difference of manufacture showed varied biological potency. Conclusions: This perhaps indicates loss of effectiveness due to change from ACTH 1–24 to ACTH 1–18 to ACTH 1–10 in descending order.

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Published

21-05-2018

How to Cite

1.
Ahmed M, Hasan R, Ahmad M. EFFECTS OF PROLONGED ADMINISTRATION OF LARGE DOSES OF ACTH ON BUFO MELANOSTICTUS TADPOLES. Pak J Phsyiol [Internet]. 2018 May 21 [cited 2024 Nov. 21];1(1-2). Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/576

Issue

Vol. 1 No. 1-2 (2005): Pakistan Journal of Physiology

Section

Original Article

License

Pakistan Journal of Physiology, Pak J Physiol, PJP is FREE for research and academic purposes. It can be freely downloaded and stored, printed, presented, projected, cited and quoted with full reference of, and acknowledgement to the author(s) and the PJP. The contents are published with an international CC-BY-ND-4.0 License.