ANTICARDIOLIPIN ANTIBODIES IN WOMEN HAVING RECURRENT SPONTANEOUS ABORTIONS

Authors

  • Haji Khan Khoharo Assistant Professor/Assistant Director Postgraduate Studies, Faculty of Medicine and Allied Medical Sciences, Isra University, Hyderabad, Pakistan
  • Ghulam Shah Nizamani Dept of Pathology, Isra University, Hyderabad, Pakistan
  • Rashid Ahmed Memon Dept of Pathology, Isra University, Hyderabad, Pakistan
  • Navaid Kazi Dept of Physiology, Isra University, Hyderabad, Pakistan
  • Sumayya Kazi Department of Biochemistry, Isra University, Hyderabad, Pakistan

Keywords:

Anticardiolipin antibodies, abortion, platelet count, prothrombin time, activated partial thromboplastin time

Abstract

The present study was conducted to analyze Anticardiolipin antibodies in women with recurrent spontaneous abortion. Methods: This was a case control study conducted from January to December 2013. A sample of 136 women, comprising of 68 cases and equal number of controls was selected according to inclusion and exclusion criteria. Strict history protocol was mandatory for women with recurrent spontaneous abortions. Women with history of immune, rheumatic, endocrine and thrombo-embolic disorders were excluded. Patients were selected through non-probability purposive sampling. Anticardiolipin antibodies were estimated by ELISA method. Data were analysed on SPSS-21. Results: Anticardiolipin antibodies were detected in 16.19% and 4.41% in cases and controls respectively. Mean serum levels of anticardiolipin antibodies were 9.15±3.73 and 7.35±2.74 RU/ml respectively. Platelet counts, prothrombin and activated partial thromboplastin revealed no significant differences between groups. Conclusion: Anticardiolipin antibodies were detected in women with recurrent spontaneous abortions.

 

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Published

30-09-2015

How to Cite

1.
Khoharo HK, Nizamani GS, Memon RA, Kazi N, Kazi S. ANTICARDIOLIPIN ANTIBODIES IN WOMEN HAVING RECURRENT SPONTANEOUS ABORTIONS. Pak J Phsyiol [Internet]. 2015 Sep. 30 [cited 2024 May 23];11(3):38-9. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/557