PREVALENCE OF COMPLICATIONS IN TYPE 2 DIABETES MELLITUS PATIENTS

Authors

  • Muhammad Ishaq Department of Physiology, Bannu Medical College, Bannu
  • Ghulam Jillani Khan Department of Physiology, Khyber Medical College, Peshawar
  • Shafiq ur Rahman Department of Physiology, Shaikh Zayed, Federal Postgraduate Medical Institute, Lahore, Pakistan
  • Sibgha Zulfiqar Department of Physiology, Shaikh Zayed, Federal Postgraduate Medical Institute, Lahore, Pakistan

Keywords:

Intermittent Claudication, Peripheral Neuropathies and Type 2 Diabetes Mellitus

Abstract

Background: Intermittent claudication mainly attributable to peripheral arterial disease is the experiencing of pain in legs, especially calf muscles, during walking and diabetic peripheral neuropathies are the commonest sequelae of diabetes mellitus. Diabetic peripheral neuropathies affect up to 50% of US patients with type 1 and type 2 diabetes mellitus. The purpose of the current study was to know about the prevalence of complications in type 2 diabetics in Lahore, Pakistan. Methods: The study was conducted at Shaikh Zayed Federal Postgraduate Medical Institute, Lahore, from 2008 to 2010. A total of 150 patients, aged ≥40 years with type 2 diabetes mellitus, were selected from the Diabetic Clinic, Cardiology Unit, and Biochemistry Department of the Institute. The subjects were equally divided into uncomplicated (n=75) and complicated (n=75) groups. Blood pressures, ABI, BMI and neurological symptoms of each patient were recorded consequently. The ‘Edinburgh Claudication Questionnaire’ was used to assess intermittent claudication. The urine of each patient was tested for microalbuminuria to label him as complicated type 2 diabetic or otherwise. Results: In both groups about 8% individuals experienced generalised pain and 3% felt numbness. Tingling sensations in the uncomplicated group were experienced by none but 2.7% of the individuals in the complicated group complained about the ailment. No patient was suffering from intermittent claudication in the uncomplicated group but 6.7% of the individuals in the complicated group reported the problem. This was the only complaint where the difference between the groups was significant statistically (p<0.05). Conclusion: The occurrence of complications particularly intermittent claudication in type 2 diabetics is more frequent compared to uncomplicated type 2 diabetes mellitus patients.

Pak J Physiol 2013;9(2):35–7

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References

1. Selvin E, Erlinger TP. Prevalence of and risk factors for peripheral arterial disease in the United States: results from the National Health and Nutrition Examination Survey. 1999-2000. Circulation 2004;110:738–43.
2. Pasternak RC, Criqui MH, Benjamin EJ, Fowkes FG, Isselbacher EM, McCullough PA, et al; American Heart Association. Atherosclerotic Vascular Conference: Writing Group I. epidemiology. Circulation 2004;109:2605–12.
3. Akram J, Aamir AU, Basit A, Qureshi MS, Mehmood T, Shahid SK, et al. Prevalence of peripheral arterial disease in type 2 diabetics in Pakistan. J Pak Med Assoc 2011;61(7):644–8.
4. Muller MD, Reed AB, Leuenberger UA, Sinoway LI. Physiology in Medicine: Peripheral Arterial Disease. J Appl Physiol 2013;115(9):1219–26.
5. Edmundsson D, Svensson O, Toolanen G. Intermittent claudication in diabetes mellitus due to chronic exertional compartment syndrome of the leg: an observational study of 17 patients. Acta Orthop 2008;79(4):534–9.
6. Tucker AK. Chronic exertional compartment syndrome of the leg. Curr Rev Musculoskelet Med 2010;3(1–4): 32–7.
7. Pasnoor M, Dimachkie MM, Kluding P, Barohn RJ. Diabetic neuropathy part 1: overview and symmetric phenotypes. Neurol Clin 2013;31(2):425–45.
8. Hartemann A, Attal N, Bouhassira D, Dumont I, Gin H, Jeanne S, et al. Painful diabetic neuropathy: diagnosis and management. Diabetes Metab 2011;37(5):377–88.
9. Boulton AJ, Vinik AI, Arezzo JC, Bril V, Feldman EL, Freeman R; American Diabetes Association. Diabetic neuropathies. Diabetes Care 2005;28(4):956–62.
10. Leng G, Fowkes F. The Edinburgh claudication questionnaire: an improved version of the WHO/ROSE questionnaire for use in epidemiological surveys. J Clin Epidemiol 1992;45:1101–9.
11. Jensen SA, Vatten LJ, Myhre HO. The association between diabetes mellitus and the prevalence of intermittent claudication: the HUNT study. Vasc Med 2008;13:239–44.
12. Harris M, Eastman R, Cowie C. Symptoms of sensory neuropathy in adults with NIDDM in the US population. Diabetes Care 1993;16(11):1446–52.
13. McBride MR, Mistretta CM. Light Touch Thresholds in diabetic patients. Diabetes Care 1982;5(3):311–5.
14. Vinik AI, Holland MT, Le Beau JM, Liuzzi FJ, Stansberry KB, Colen LB. Diabetic neuropathies. Diabetes Care 1992;15(12):1926–75.
15. Asad A, Hameed MA, Khan UA, Butt MU, Ahmed N, Nadeem A. Comparison of nerve conduction studies with diabetic neuropathy symptom score and diabetic neuropathy examination score in type-2 diabetics for detection of sensorimotor polyneuropathy. J Pak Med Assoc 2009;59:594–8.

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Published

31-12-2013

How to Cite

1.
Ishaq M, Khan GJ, Rahman S ur, Zulfiqar S. PREVALENCE OF COMPLICATIONS IN TYPE 2 DIABETES MELLITUS PATIENTS. Pak J Phsyiol [Internet]. 2013 Dec. 31 [cited 2024 Mar. 28];9(2):35-7. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/388