HISTOPATHOLOGICAL SPECTRUM OF OVARIAN EPITHELIAL TUMOURS: A CROSS-SECTIONAL STUDY
DOI:
https://doi.org/10.69656/pjp.v25i1.1717Keywords:
Ovarian Cancer, Ovarian Epithelial Cancers, Histopathology, Benign, MalignantAbstract
Background: Ovarian cancer (OC) poses a significant health burden, ranking 8th in women’s cancers globally. Ovarian epithelial cancers (OEC) can present in a number of histopathologically distinct benign and malignant patterns. This study aims to assess the histopaythological characteristics of ovarian epithelial tumours in our local setting. Methods: This retrospective cross-sectional study, conducted at Ayub Medical College, Abbottabad, from Jan 2022 to Dec 2023, included 111 patients with histopathologically confirmed ovarian epithelial lesions. All biopsy records of OC during the study periods were retrieved and assessed for histopathological diagnosis. Confirmed cases of OEC were re-examined and included in the study. Records of patients’ associated demographic data were obtained from HMIS of Ayub Teaching Hospital. Data were analysed on SPSS-27. Results: The mean age at diagnosis was 53.44±10.52 years, with the majority (73, 65.8%) being multipara and having unilateral lesions. Serous cystadenoma emerged as the most prevalent (42, 37.8%) benign tumour, while serous carcinoma dominated (22, 19.8%) malignant cases. Family history emerged as a significant factor, with 60.5% of malignant cases having a positive family history (p<0.001). Stratification by age at diagnosis, menarche, and menopause revealed no statistically significant difference between benign and malignant lesions in all strata. Conclusions: Serous cystadenoma is the most common benign tumour while serous carcinoma is the most common ovarian epithelial malignancy in Hazara division. The predominance of serous cystadenoma and serous carcinoma underscores the need for further exploration of familial risk factors.
Pak J Physiol 2025;21(1):25–8, DOI: https://doi.org/10.69656/pjp.v21i1.1717
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Copyright (c) 2025 Sidra Maqbool Khan, Muhammad Tariq, Shagufta Naeem, Syed Meesam Mehdi, Anila Riyaz, Fouzia Jehangir

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