EFFECT OF VITAMIN D SUPPLEMENTATION ON LIPID PROFILE IN PATIENTS OF ACUTE CORONARY SYNDROME

Authors

  • Sidra Jabeen HITEC-Institute of Medical Sciences, Taxila Cantt., Pakistan
  • Humaira Fayyaz Khan Department of Physiology, Riphah International University Al-Meezan Campus, Rawalpindi, Pakistan
  • Sana Majeed Department of Physiology, Riphah International University Al-Meezan Campus, Rawalpindi, Pakistan
  • Mehvish Ashfaq Department of Physiology HITEC-Institute of Medical Sciences, Taxila Cantt., Pakistan
  • Hina Munir Department of Physiology, AJK Medical College, Muzaffarabad, Pakistan
  • Saira Safder Department of Physiology, Islamabad Medical and Dental College, Islamabad, Pakistan.

DOI:

https://doi.org/10.69656/pjp.v18i1.1406

Keywords:

Vitamin D, Total Cholesterol, TG, HDL, LDL, Cholesterol ratio, Acute Coronary Syndrome

Abstract

Background: Association studies have proposed a link between vitamin D levels and lipid profile. Deranged lipid profile is hallmark of acute coronary syndrome (ACS) patients. The present study was aimed to determine the role of vitamin D supplementation in improving the lipid profile of ACS patients. Methods: A total of 40 patients diagnosed with ACS were included in the study. They were divided into control (n=20) and experimental group (n=20). Experimental group received vitamin D supplementation as a single dose of 200,000 IU orally. Baseline vitamin D levels and lipid profile were done. Post sampling was done after an interval of 2 months for the same parameters. Results: The serum levels of cholesterol were decreased significantly in the experimental group (p=0.05) while TG levels showed trend towards a decrease (p=0.084). Serum HDL was increased (p=0.03), while serum LDL (p=0.04) and cholesterol ratio (p=0.012) were decreased significantly. Conclusion: Vitamin D supplementation improved lipid profile in ACS patients, and can be used as adjunct therapy in ACS patients.

Pak J Physiol 2022;18(1):32?5

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Published

31-03-2022

How to Cite

1.
Jabeen S, Khan HF, Majeed S, Ashfaq M, Munir H, Safder S. EFFECT OF VITAMIN D SUPPLEMENTATION ON LIPID PROFILE IN PATIENTS OF ACUTE CORONARY SYNDROME. Pak J Phsyiol [Internet]. 2022 Mar. 31 [cited 2024 Dec. 22];18(1):32-5. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/1406

Issue

Vol. 18 No. 1 (2022): Pakistan Journal of Physiology

Section

Original Article

License

Pakistan Journal of Physiology, Pak J Physiol, PJP is FREE for research and academic purposes. It can be freely downloaded and stored, printed, presented, projected, cited and quoted with full reference of, and acknowledgement to the author(s) and the PJP. The contents are published with an international CC-BY-ND-4.0 License.