OLFACTORY ENSHEATHING CELLS IN THE REPAIR OF SPINAL CORD INJURY
DOI:
https://doi.org/10.69656/pjp.v10i3-4.760Keywords:
Spinal cord repair, Olfactory bulb, Spinal Cord Injury, Olfactory ensheathing cellsAbstract
Olfactory Ensheathing Cells (OCEs) are a type of glial cells that ensheath the non myelinated olfactory neurons. They have unique property of assisting regeneration of olfactory neurons after they get injured. These cells are being tested for axonal regeneration. They are the top contenders for cell transplantation based treatment of spinal cord damage. After the animal studies, now a day a number of centres are trying to use the technique in humans. Getting autologous olfactory bulb is cumbersome but getting it from human cadavers has its own limitations due to transplant rejection. After establishing the technique of autologous cell transplantation, a hospital in Poland has reported success in a person with four years old spinal cord injury. There is a need to replicate this technique in various centres so that the procedure is established.
Pak J Physiol 2014;10(3–4):1–2
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Pakistan Journal of Physiology, Pak J Physiol, PJP is FREE for research and academic purposes. It can be freely downloaded and stored, printed, presented, projected, cited and quoted with full reference of, and acknowledgement to the author(s) and the PJP. The contents are published with an international CC-BY-ND-4.0 License.