MILD CHRONIC PERIODONTITIS: A POSSIBLE THREAT TOWARDS CVD IN MALES WITH RAISED C-RP

Abstract

Chronic Periodontitis, is a globally common oral problem. Lately, the association between periodontitis and cardiovascular disease has received greater attention, though there is paucity of database in local population. The objective of this study was to explore the possible association of chronic periodontitis with cardiovascular disease by elevating C-reactive proteins (C-RP), and to study any influence of gender, in the study population. Methods: This was an analytical cross-sectional study and involved 75 patients (46 males and 29 females) volunteering their blood samples, out of which 55% carried both cardiac and periodontal diseases, whereas 45% had periodontitis alone. Serum level of C-RP was assessed by performing sandwich ELISA. Results: In both genders C-RP was higher in case of mild periodontitis as compared to severe one. In males raised serum level of C-RP was noticed in patients of cardiovascular disease along with periodontitis in comparison to those who had only chronic periodontitis. Male and female patients who had chronic periodontitis alone showed significantly less concentration of C-RP as compared to patients with chronic periodontitis along with heart disease. Highest level of C-RP was seen in both genders, with cardiac disease accompanied with mild periodontitis rather than with severe periodontitis. Furthermore, in all categories females showed relatively low C-RP. Conclusion: Mild state of chronic periodontitis is more pronounced threat towards cardiovascular disease, especially among males.