PREVALENCE OF DIFFERENT TYPES OF PEPTIC ULCER DISEASE AND TREATMENT MODALITIES USED BY PATIENTS IN HYDERABAD, SINDH

Authors

  • Muhammad Noman Rashid Department of Physiology, Shaheed Mohtarama Benazir Bhutto Medical College, Karachi
  • Ali Muhammad Soomro Department of Physiology
  • Naseem Aslam Channa Institute of Biochemistry, University of Sindh, Jamshoro, Pakistan
  • Zulfiqar Ali Laghari Department of Physiology

DOI:

https://doi.org/10.69656/pjp.v12i1.410

Keywords:

Peptic ulcer, Gastric ulcer, Duodenal Ulcer, Homeopathy, Allopathy, Herbal Medicine, Helicobacter pylori, Non-steroidal anti-inflammatory drugs

Abstract

Background: Peptic ulcer is mucosal lesion of the stomach or duodenum in which acid and pepsin play major pathogenic role. The major forms of peptic ulcer are gastric ulcer and duodenal ulcer, often caused by Helicobacter pylori, non-steroidal anti-inflammatory drugs (NSAIDs), physiological stress and smoking. The objective of this was to assess the prevalence of different types of peptic ulcer and treatment modalities in peptic ulcer patients. Methods: A total of 425 patients of different age groups were selected from different areas of Hyderabad city having peptic ulcer. There were 166 (39%) male and 259 (61%) females. Data were collected on a questionnaire. Subjects were divided into 5 age groups. Results: Peptic ulcer was more prevalent in age group 20–30 years and mostly found in females (60%) compared to males (40%). Gastric ulcer was seen mostly (68%) compared to duodenal ulcer (32%). The tendency of treatment type came out to be allopathic 38%, homeopathic 4%, and herbal 4%. The tendency of combination therapy was allopathic+homeopathic 34%, homeopathic+herbal 4%, allopathic+herbal 12%, and allopathic+homeopathic+herbal 4%. Conclusion: Gastric ulcer is more common than duodenal ulcer in Hyderabad that is in contrast to reported data. The patients suffering from either types of ulcer preferred allopathic treatment followed by homoeopathy and herbal medication.

Pak J Physiol 2016;12(1):6–9

Downloads

Download data is not yet available.

References

1. Kim YH, Lee JH, Lee SS, Cho EE, Oh YL, Son HJ, et al. Long term stress and Helicobacter pylori infection independently induce gastric mucosal lesion in C57BL/mice. Scand J Gastroenterol 2002;37( 11):12529–64.
2. Andersen IB, Jorgensen T, Bonnevie O, Gronbaek M, Sorensen TI. Smoking and alcohol intake as risk factors for bleeding and perforated peptic ulcers: a population-based cohort study. Epidemiology 2000;11(4):434–9.
3. Arroyo MT, Forne M, de Argila CM, Feu F, Arenas J, de la Vega J, et al. The prevalence of peptic ulcer not related to Helicobacter pylori or NSAIDs use is negligible in southern Europe. Helicobacter 2004;9(3):249–54.
4. Barbara P, Nuno L, Ceu F, Fatima C, Leonar D, Henrique B. Smoking, Helicobacter pylori virulence and type of intestinal metaplasia in Portuguese males. Cancer Epidemiol Biomarkers Prev 2007;16(2):322–6.
5. Bjorkmann DJ. NSAIDs and Helicobacter pylori: A dangerous Combination? Lancet 2002;359:3–4.
6. Bopana N, Saxena S. Asparagus racemosus–ethnopharmacological evaluation and conservation needs. J Ethnopharmacol 2007;110(1):1–15.
7. Dore MP, Graham DY. Pathogenesis of duodenal ulcer disease: the rest of the story. Baillieres Best Pract Res Clin Gastroenterol 2000;14:97–107.
8. Yakoob J, Abid S, Jafri W, Abbas Z, Mumtaz K, Hamid S, et al. Low rate of recurrence of Helicobacter pylori infection in spite of high clarithromycin resistance in Pakistan. BMC Gastroenterology 2013;13:33.
9. Niaz Ali, Abid Ullah, Sohail Akhtar, Syed Wadood Ali Shah, Muhammad Junaid. Factors associated with peptic ulcer: a single centre experience at tertiary care hospital of Khyber Pakhtunkhwa. Khyber Med Uni J 2013;5(1):18–21.
10. Hozawa A, Houston T, Steffes MW, Widome R, Williams OD, Iribarren C, et al. The association of cigarette smoking with self-reported disease before middle age: The Coronary Artery Risk Development in Young Adults (CARDIA) study. Prev Med 2006;42(3):193–9.
11. Habif TM. Principles of diagnosis and anatomy. In: Habif TP (Ed). Clinical Dermatology. 5th ed. Hiladelphia, Pa: Mosby Elsevier; 2009: Chap 1.
12. Helicobacter pylori in Peptic Ulcer Disease. National Institutes of Health Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease. JAMA 1994;272(1):65–9.
13. Higham J, Kang JY, Majeed A. Recent trends in admissions and mortality due to peptic ulcer in England: increasing frequency of haemorrhage among older subjects. Gut 2002;50(4):460–4.
14. Hamid S, Yakoob J, Jafri W, Islam S, Abid S, Islam M. Frequency of NSAIDs induced peptic ulcer disease. J Pak Med Assoc 2006;56(5):218–22.
15. Mohammad Nawaz, Mohammad Jehanzaib, Khalid Khan, Muhammad Zari. Role of barium meal examination in diagnosis of peptic ulcer. J Ayub Med Coll Abbottabad 2008;20(4):59–61.

Downloads

Published

31-03-2016

How to Cite

1.
Rashid MN, Soomro AM, Channa NA, Laghari ZA. PREVALENCE OF DIFFERENT TYPES OF PEPTIC ULCER DISEASE AND TREATMENT MODALITIES USED BY PATIENTS IN HYDERABAD, SINDH. Pak J Phsyiol [Internet]. 2016 Mar. 31 [cited 2024 Dec. 22];12(1):6-9. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/410