EFFECT OF INSECTICIDES (PYRETHROIDS) ON LUNG FUNCTION PARAMETERS IN SCHOOL CHILDREN

Authors

  • Padma Rathore Department of Physiology, Jinnah Sindh Medical University, Karachi
  • Sikandar Ali Sheikh Quetta Institute of Medical Sciences, Quetta
  • Ruqaya . Baqai Medical University, Karachi, Pakistan
  • Nida Lathiya Baqai Medical University, Karachi, Pakistan

DOI:

https://doi.org/10.69656/pjp.v13i1.261

Keywords:

Pyrethrin (Natural), Pyrethroid (Synthetic), Forced Vital Capacity, FVC, Forced Expiratory Volume in 1st second (FEV1), Peak Expiratory Flow (PEF)

Abstract

Background: Mosquito repellants and many other insecticides contain Pyrethrins and Pyrethroids. Pyrethroids are the most commonly used household insecticides derived from Chrysanthemum flowers. These insecticides can cause several clinical problems like allergies, asthma attacks, wheezing and bronchospasm. Despite all associated side effects, pyrethroids are still considered to be least toxic. In the present study the effects of pyrethroids on lung function parameters of school children were analyzed. Method: The study was conducted at Government Girls Primary School, Sita Nagar, Karachi including 50 children 6–10 years old. They were divided equally into two groups. Group A (exposed to insecticidal spray) and group B (exposed to combustible coil). Result: The correlations between the insecticides (pyrethroids), and the spirometry variables (FVC, FEV1, PEF, and FEV1/FVC ratio) by linear regression analysis confirmed that pyrethroids had a strong correlation with the spirometric values under study exemplified by the significant decrease in FVC and FEV1 after exposure to insecticidal spray. Conclusion: Highly significant values of FVC and FEV1 were observed after combustible mosquito coil exposure. There was no association between FEV1/FVC ratio, PEF, and exposure to insecticidal spray and mosquito coils.

Pak J Physiol 2017;13(1):26–9

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Published

31-03-2017

How to Cite

1.
Rathore P, Sheikh SA, . R, Lathiya N. EFFECT OF INSECTICIDES (PYRETHROIDS) ON LUNG FUNCTION PARAMETERS IN SCHOOL CHILDREN. Pak J Phsyiol [Internet]. 2017 Mar. 31 [cited 2024 Nov. 21];13(1):26-9. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/261

Issue

Vol. 13 No. 1 (2017): Pakistan Journal of Physiology

Section

Original Article

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