AETIOLOGICAL FACTORS OF NON-TRAUMATIC DUODENAL PERFORATION

Authors

  • Muhammad Siddique Khan Department of Surgery, Ayub Teaching Hospital, Abbottabad
  • Junaid Zeb Department of Surgery, Ayub Teaching Hospital, Abbottabad
  • Ashfaq Ahmad Department of Surgery, Ayub Teaching Hospital, Abbottabad
  • Amer Zaman Department of Surgery, Ayub Teaching Hospital, Abbottabad

DOI:

https://doi.org/10.69656/pjp.v13i1.259

Keywords:

Duodenal perforation, H. pylori, NSAIDS, Ulcer, Bleeding

Abstract

Background: Each year peptic ulcer disease affects 4 million people around the world. Perforation of the duodenum due to peptic ulcer remains a considerable medical problem causing high morbidity and mortality. This study aimed to determine the major aetiological factors of non-traumatic duodenal perforations. Methods: It was a cross-sectional study carried out in Surgical ‘B’ Unit, Ayub Teaching Hospital, Abbottabad, Pakistan from 15th Jun 2012 to 15th May 2015. One hundred and eighty-six patients were recruited for the study. Data was collected and analysed on SPSS-23. Results: Mean age of the study participants was 48.4±7.14 years. Male to female ratio was 3:5. The main causative agent was H. pylori (54.30%), 22.04% were smokers, 6.99% had history of using NSAIDS, and 31 (16.67%) patients had more than one causative factor. There was strong association found between age groups and socio-economic status (p=0.004), and literacy level of the respondents (p=0.003). Conclusion: Non-perforated duodenal ulcers are significantly associated with middle-aged people, low socioeconomic status, NSAIDS, smoking, and H. pylori.

Pak J Physiol 2017;13(1):19–21.

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Published

31-03-2017

How to Cite

1.
Khan MS, Zeb J, Ahmad A, Zaman A. AETIOLOGICAL FACTORS OF NON-TRAUMATIC DUODENAL PERFORATION. Pak J Phsyiol [Internet]. 2017 Mar. 31 [cited 2024 Nov. 21];13(1):19-21. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/259

Issue

Vol. 13 No. 1 (2017): Pakistan Journal of Physiology

Section

Original Article

License

Pakistan Journal of Physiology, Pak J Physiol, PJP is FREE for research and academic purposes. It can be freely downloaded and stored, printed, presented, projected, cited and quoted with full reference of, and acknowledgement to the author(s) and the PJP. The contents are published with an international CC-BY-ND-4.0 License.