EFFECT OF ALMONDS AND ATENOLOL ON SERUM LUTEINIZING HORMONE LEVEL IN MALE BALB-C MICE

Authors

  • Irum Rehman Margalla Institute of Health Scienes, Rawalpindi
  • Shakir khan
  • ifra ashraf
  • ayesha naveed
  • farheen masood

DOI:

https://doi.org/10.69656/pjp.v14i3.203

Keywords:

Keywords: Prunus Amygdalis, Almonds Atenolol, Luteinizing hormone.

Abstract

Background: Along with other advantageous effects nuts are good for fertility and can improve derangements in different fertility parameters. With increasing incidence of hypertension leading to an increase in consumption of antihypertensives it is inevitable to depart their side effects. This study was designed to see the effect of administration of Prunus amygdalus, atenolol and combination of atenolol and Prunus amygdalus on level of serum luteinizing hormone (LH) in male Balb-C mice. Methods: This experimental study was conducted from December 2013 to June 2014. One hundred and twenty mice fulfilling inclusion criteria were divided into 4 groups of 30 mice each. Group A served as control group, group B mice were given atenolol, group C mice were given extract of almonds and group D mice were given atenolol and almonds. After the completion of 3 months, blood sampling was done and serum LH was measured. Data was analyzed on SPSS-17, Mean±SD was calculated for luteinizing hormone levels. One-way ANOVA was applied and p≤0.05 was considered significant. Results: The mean value of serum LH in group B (Atenolol treated) was found to be significantly elevated. In group C (Almonds) serum LH was decreased but not significantly. Mean serum LH level in group D (Atenolol+Almond) was raised as compared to control group, but not significantly. Conclusion: Administration of Prunus amygdalis does not affect serum LH but atenolol causes a rise in serum LH.

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Pak J Physiol 2018;14(3)

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Published

14-08-2018

How to Cite

1.
Rehman I, khan S, ashraf ifra, naveed ayesha, masood farheen. EFFECT OF ALMONDS AND ATENOLOL ON SERUM LUTEINIZING HORMONE LEVEL IN MALE BALB-C MICE. Pak J Phsyiol [Internet]. 2018 Aug. 14 [cited 2024 Dec. 22];14(3):37-40. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/203

Issue

Vol. 14 No. 3 (2018): Pakistan Journal of Physiology

Section

Original Article

License

Pakistan Journal of Physiology, Pak J Physiol, PJP is FREE for research and academic purposes. It can be freely downloaded and stored, printed, presented, projected, cited and quoted with full reference of, and acknowledgement to the author(s) and the PJP. The contents are published with an international CC-BY-ND-4.0 License.