COLONOSCOPY-BASED DIAGNOSTIC TRENDS IN COLORECTAL DISEASES: EVIDENCE FROM A TERTIARY CARE HOSPITAL IN KARACHI, PAKISTAN

Authors

  • Aina Marzia Syed 3rd Year MBBS Student, Jinnah Sindh Medical University, Karachi, Pakistan
  • Marium Waqar Department of Medicine, Jinnah Sindh Medical University/Jinnah Postgraduate Medical Centre , Karachi, Pakistan
  • Zeeshan Ali Department of Medicine, Jinnah Sindh Medical University/Jinnah Postgraduate Medical Centre , Karachi, Pakistan
  • Shabnam Naveed Department of Medicine, Jinnah Sindh Medical University/Jinnah Postgraduate Medical Centre, Karachi, Pakistan
  • Saleem Shahzad Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi, Pakistan
  • Syed Masroor Ahmed Department of Medicine, Jinnah Sindh Medical University/Jinnah Postgraduate Medical Centre, Karachi, Pakistan

DOI:

https://doi.org/10.69656/pjp.v21i4.1848

Keywords:

Colonoscopy, Hemorrhoids, colorectal cancer, Inflammatory bowel disease

Abstract

Background: Colonoscopy is an essential diagnostic and therapeutic modality for evaluating a wide range of colorectal diseases, including polyps, inflammatory bowel disease (IBD), intestinal tuberculosis, haemorrhoids, and colorectal malignancies. This study aims to evaluate the spectrum of colonoscopic findings at a tertiary care hospital in Karachi and explore their association with patients’ age and gender. Methods: It was a retrospective cross-sectional review conducted in the endoscopy suite of Medical Unit III, Ward 7, Jinnah Postgraduate Medical Centre, Karachi. The data of 527 patients who underwent colonoscopy from 1st Jan 2020 to 31st Dec 2022 was recorded. Collected data was analysed through SPSS-25, and data were tabulated as frequencies and percentages. Results: Out of a total of 527 patients of mean age of 37.09 years, 209 (39.7%) were female patients. Abdominal pain 168 (31.9%), followed by per rectal bleed 165 (31.3%) were the commonest presenting complaints, 83 (15.7%) patients had chronic diarrhoea. The most frequent finding of colonoscopy was internal haemorrhoids in 140 (26.6%) patients, followed by IBD 44 (8.4%). Intestinal tuberculosis (TB) was 25 (4.7%), colon cancer was 17 (3.2%), rectal cancer was 13 (2.5%), and anal cancer was 7 (1.3%). Conclusion: The most common colonoscopic finding was internal haemorrhoids, followed by IBD and intestinal tuberculosis. Malignancies including colon, rectal, and anal cancers were also identified, though less frequently. These findings emphasize the diverse spectrum of colorectal diseases in clinical practice.

Pak J Physiol 2025;21(4):15–8, DOI: https://doi.org/10.69656/pjp.v21i4.1848

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References

Colorectal Conditions Gastroenterology [Internet]. Intermountain Healthcare. Available from: https://intermountainhealthcare.org/ services/gastroenterology/conditions/colorectal-conditions/ [cited 2023 Sep 8]

Milla PJ, Stauffer CM, Pfeifer C. Colonoscopy. In: Spitz L, Davenport M, Coran A. (Eds). Operative Pediatric Surgery. 6th ed. London: Hodder Arnold; 2006. p. 601–10.

Mohammad S, Rind GH, Shah IA, Baloch I, Shah AA, Lakho S, et al. Colonoscopy findings: A single institution study from Pakistan. Cureus 2019;11(11):e6162.

Toyoshima O, Nishizawa T, Yoshida S, Matsuno T, Miyoshi K, Naito E, et al. Hemorrhoids as a risk factor for colorectal adenomas on colonoscopy. Endosc Int Open 2023;11(5):E497–503.

Nagar AB. Isolated colonic ulcers: diagnosis and management. Curr Gastroenterol Rep 2007;9(5):422–8.

Bernstein S. Causes of colon erosions. [Internet]. WebMD. Available from: https://www.webmd.com/ibd-crohns-disease/ causes-colon-erosion [cited 2023 Sep 8].

Passos MAT, Chaves FC, Chaves-Junior N. The importance of colonoscopy in inflammatory bowel diseases. Arq Bras Cir Dig 2018;31(2):e1374.

Alvares JF, Devarbhavi H, Makhija P, Rao S, Kottoor R. Clinical, colonoscopic, and histological profile of colonic tuberculosis in a tertiary hospital. Endoscopy 2005;37(4):351–6.

Huck MB, Bohl JL. Colorectal polyps and polyposis syndromes: Colonic polyps: diagnosis and surveillance. Clin Colon Rectal Surg 2016;29(4):296–305.

Prenner S, Levitsky J. Comprehensive review on colorectal cancer and transplant. Am J Transplant 2017;17(11):2761–74.

Panteris V, Haringsma J, Kuipers EJ. Colonoscopy perforation rate, mechanisms and outcome: from diagnostic to therapeutic colonoscopy. Endoscopy 2009;41(11):941–51.

Saltzman JR, Cash BD, Pasha SF, Early DS, Muthusamy VR, Khashab MA, et al. Bowel preparation before colonoscopy. Gastrointest Endosc 2015;81(4):781–94.

Baron TH, Smyrk TC, Rex DK. Recommended intervals between screening and surveillance colonoscopies. Mayo Clin Proc 2013;88(8):854–8.

Thursby E, Juge N. Introduction to the human gut microbiota. Biochem J 2017;474(11):1823–36.

Kim YS, Kim N, Kim GH. Sex and gender differences in gastroesophageal reflux disease. J Neurogastroenterol Motil 2016;22(4):575–88.

Kozan R, Y?lmaz TU, Ba?tu?ral U, Kerimo?lu U, Yavuz Y. Factors affecting successful colonoscopy procedures: single-center experience. Turk J Surg 2017;33(3):173–7.

Bowles CJ, Leicester R, Romaya C, Swarbrick E, Williams CB, Epstein O. A prospective study of colonoscopy practice in the UK today: Are we adequately prepared for national colorectal cancer screening tomorrow? Gut 2004;53(2):277–83.

Riaz R, Masood N, Benish A. Red flag symptoms: detailed account of clinicopathological features in young-onset colorectal cancer. Intest Res 2017;15(2):203–7.

Ali F, Aamir N, Hassan MK. Colonoscopic findings in patients presenting with lower gastrointestinal bleeding at a tertiary care hospital. Rawal Med J 2023;48(2):324–6.

Sherwani U, Azmat S, Ejaz M, Ibrahim M, Safdar S. Kousar R. Frequency of solitary rectal ulcer syndrome among patients presenting with bleeding per rectum at a tertiary care hospital. Biol Clin Sci Res J 2023;2023(1):477.

Ejaz Z, Khan SU, Rehman RU, Jibran MS. Solitary rectal ulcer syndrome in patients presenting with lower gastrointestinal bleeding: A tertiary-care hospital experience. Cureus 2023;15(2):e35247.

Kutluana U. Incidence of solitary rectal ulcer syndrome in patients undergoing colonoscopy. Haydarpasa Numune Med J 2018;58(3):146–51.

Enck P, Aziz Q, Barbara G, Farmer AD, Fukudo S, Mayer EA, et al. Irritable bowel syndrome. Nat Rev Dis Primers 2016;2:16014.

Caviglia GP, Garrone A, Bertolino C, Vanni R, Bretto E, Poshnjari A, et al. Epidemiology of inflammatory bowel diseases: A population study in a healthcare district of North-West Italy. J Clin Med 2023;12(2):641.

Alsumait AF, Al-Farsi YM, Waly MI, Al-Qarshoobi IS, Al-Adawi S, Albali NH, et al. Hospital prevalence of colorectal cancer among colonoscopy recipients attending a tertiary hospital in Oman: A cross-sectional study. Sci World J 2020;2020:5863126.

National Cancer Institute. SEER Cancer Stat Facts: Colorectal Cancer [Internet]. Bethesda (MD): SEER Program; 2024. Available from: https://seer.cancer.gov/statfacts/html/colorect.html

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Published

31-12-2025

How to Cite

1.
Syed AM, Waqar MF, Ali Z, Naveed S, Shahzad S, Ahmed SM. COLONOSCOPY-BASED DIAGNOSTIC TRENDS IN COLORECTAL DISEASES: EVIDENCE FROM A TERTIARY CARE HOSPITAL IN KARACHI, PAKISTAN. Pak J Phsyiol [Internet]. 2025 Dec. 31 [cited 2026 Jan. 3];21(4):15-8. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/1848