EFFICACY OF ENHANCED PREOPERATIVE MANAGEMENT FOR NON-PROGRESSION IN MEIBOMIAN GLAND DYSFUNCTION AFTER CATARACT SURGERY: A RANDOMIZED CONTROLLED TRIAL
DOI:
https://doi.org/10.69656/pjp.v20i2.1674Keywords:
Dysfunction, Meibomian Gland, PreoperativeAbstract
Background: Cataract surgery may alter proper functioning of meibomian glands and result in worsening of glandular dysfunction. The role of combined postop and routine 3 days preoperative treatment of meibomian gland disease (MGD) after cataract surgery has been studied but the role of enhanced 2 weeks preoperative treatment has yet to be evaluated. The objective of this study was to compare the efficacy of enhanced preoperative treatment for 2 weeks and routine preoperative treatment for 3 days alone in non-progression of MGD to severe stages after cataract surgery. Methods: This randomized controlled study was conducted at Ophthalmology Department, Ayub Teaching Hospital Abbottabad from 1st March 2022 to 31st July 2023. The sample size was 150 eyes (75 in each group) selected using consecutive sampling. Group A was given enhanced 2 weeks preoperative treatment while the group B was given routine 3 days pre-operative treatment only. Success of pre-operative treatment was regarded as non-progression to severe stages postoperatively from baseline. Data analysis was done using SPSS-24. Results: The efficacy of enhanced 2 weeks preoperative treatment was 69 (87.3%) at 1 month, and 67 (82.7%) at 3 months follow-up while efficacy of routine 3 days preoperative treatment alone was 10 (12.7%) and 14 (17.3%) at 1 and 3 months respectively with a significant difference between the groups (p<0.001). Conclusion: Enhanced 2 weeks preoperative treatment was superior to routine 3 days preoperative treatment alone in non-progression of MGD to severe stages after cataract surgery.
Pak J Physiol 2024;20(2):58-60
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