EFFECT OF HIGH FAT AND CAGED CHICKEN DIET ON OVARIAN HISTOMORPHOLOGY IN FEMALE ALBINO RATS
Keywords:
Caged chicken, High fat diet, Ovary, Histomorphology, Stroma, Hypervascularity, Polycystic ovaries, Steroid sex ormones, HyperlipidemiaAbstract
Background: Consumption of high fat diet, caged chicken meat and sedentary lifestyle have seriously increased the risks of hyperlipidema that leads to increased ovarian weight as well as ovarian stromal changes associated with difficulties in reproduction. This study is designed to compare the effects of high fat and caged chicken diet on histomorphology of ovaries of female albino rats. Methods: This study was conducted in collaboration with National Institute of Health and Anatomy Department of Islamic International Medical College, Islamabad after approval from Ethics Review Committee. The study duration was 12 months from Sep 2021 to Sep 2022, and was performed on 30 albino rats. Control group A was given standard rat diet. Experimental group B was given High Fat Diet (HFD) of 60% fat. Experimental group C was given cubes of caged chicken meat in the raw form. At the end of experiment, animals’ ovaries were collected and weighed. The samples were processed, sectioned in 5 ?m thickness, stained with H&E and observed under light microscope for stromal vascular changes and congestion. Results: The ovarian weight and stromal vascularity significantly increased in caged chicken diet group C compared to control group A and experimental group B. Conclusion: Caged chicken diet is more harmful than HFD in causing ovarian weight gain and ovarian stromal hypervascularity.
Pak J Physiol 2023;19(4):23-5
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