PREVALENCE OF DYSLIPIDEMIA AMONG PATIENTS OF POLYCYSTIC OVARIAN SYNDROME: A CROSS SECTIONAL ANALYTICAL STUDY

Authors

  • Saleha Zafar Quaid e Azam Medical College Bahawalpur
  • Tabinda Yasmin Department of Pathology, Nawab Sir Sadiq Hospital, Bahawalpur, Pakistan
  • Rabia Saeed CMH Institute of Medical Sciences Bahawalpur
  • Javaria Aslam Quaid e Azam Medical College, Bahawalpur, Pakistan
  • Tanzila Rafiq CMH Institute of Medical Sciences, Bahawalpur, Pakistan
  • Ammar Bin Saad Department of Pathology, Ayub Medical College, Abbottabad, Pakistan

Keywords:

Polycystic Ovarian Syndrome, Dyslipidemia, Metabolic Syndrome, PCOS

Abstract

Background: Polycystic ovarian disease is a genetically complicated condition, most prevalent in women of reproductive age group. It is strongly associated with obesity, dyslipidemias, and menstrual disorders. Objective of this study was to determine the prevalence of dyslipidemia in patients of polycystic ovarian syndrome (PCOS). Method: A cross-sectional analytical study was conducted at the Department of Gynaecology, Bahawal Victoria Hospital, Bahawalpur, from 1st Jan to 31st Dec 2021. All newly diagnosed patients of PCOS between the ages of 18 and 35 with a BMI <25 Kg/m2 were included in the study. Participants were divided into subgroups according to their age and BMI. The fasting lipid profile was measured through a blood sample taken from each patient after an overnight fast. Total cholesterol >200 mg/dL, LDL-C >130 mg/dL, Triglycerides >150 mg/dL, and HDL-C <40 mg/dL were labelled as dyslipidemia. Chi-square test was used to calculate and estimate the relative risk (RR) of any associations observed. Results: Among total 286 analysed patients of PCOS, mean age was 24.4±5.367 years and mean BMI was 21.01±1.912 Kg/m2. Sixty nine (24.13%) patients had dyslipidemia. Patients in the 18–27 age group and a BMI of 21–23 Kg/m2 were more likely to have dyslipidemia with PCOS, [RR 44.90; 95% CI (16.93, 119.04); p<0.001], and [RR 32.12; 95% CI (8.02, 128.61); p<0.001] respectively. Conclusion: Dyslipidemia is seen in 24.13% individuals with PCOS. Screening in routine is recommended.

Pak J Physiol 2024;20(1):19-21

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Author Biographies

Saleha Zafar, Quaid e Azam Medical College Bahawalpur

Consultant Pathologist, Quaid e Azam Medical College Bahawalpur

Tabinda Yasmin, Department of Pathology, Nawab Sir Sadiq Hospital, Bahawalpur, Pakistan

Consultant Pathologist Nawab Sir Sadiq Hospital, BWP

Rabia Saeed, CMH Institute of Medical Sciences Bahawalpur

Assistant Professor, Pathology 

Javaria Aslam, Quaid e Azam Medical College, Bahawalpur, Pakistan

Assistant Professor of Internal Medicine Quaid e Azam Medical College Bahawalpur

Tanzila Rafiq, CMH Institute of Medical Sciences, Bahawalpur, Pakistan

Assistant Professor Gynae and Obstetrics, CMH Institute of Medical Sciences Bahawalpur

Ammar Bin Saad, Department of Pathology, Ayub Medical College, Abbottabad, Pakistan

Assistant Professor Hematology Pathology Department, Ayub Medical College Abbottabad

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Published

31-03-2024

How to Cite

1.
ZAFAR S, Yasmin T, Saeed R, ASLAM J, Rafiq T, Bin Saad A. PREVALENCE OF DYSLIPIDEMIA AMONG PATIENTS OF POLYCYSTIC OVARIAN SYNDROME: A CROSS SECTIONAL ANALYTICAL STUDY. Pak J Phsyiol [Internet]. 2024 Mar. 31 [cited 2024 May 23];20(1):19-21. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/1599