Morphological analysis of astrocytoma

  • Abdul Rehman Qaisrani University of Health Sciences, Lahore, Pakistan
  • Uzma Shaheen College of Physicians and Surgeons, Pakistan
  • Sadia Nazir Dera Ghazi Khan Medical College, Dera Ghazi Khan, Pakistan
  • Naseem Jahan Dera Ghazi Khan Medical College, Dera Ghazi Khan, Pakistan
  • Muhammad Wahid Saleem Ghazi Khan Medical College, Dera Ghazi Khan, Pakistan
  • Zohaib Ashraf Ghazi Khan Medical College, Dera Ghazi Khan, Pakistan
Keywords: Pilocytic astrocytoma, Diffuse astrocytoma, Anaplastic astrocytoma, Glioblastoma multiforme, GBM

Abstract

Background: Astrocytoma is the most common brain tumour in adults. It is the second common tumour of CNS in children. The purpose of this study was to provide preliminary data on morphological patterns of astrocytoma in Pakistan. Methods: This was a descriptive cross-sectional study on diagnosed cases of astrocytoma admitted in Neurosurgery Ward, Lahore General Hospital, Pakistan. Biopsies were examined histologically using paraffin sections. Histopathological grading of astrocytoma was done according to WHO classification. Results: Out of total 40 cases, Glioblastoma multiforme (GBM) was the most common tumour accounting for 16 (40%) cases. Diffuse astrocytoma was the second common tumour seen in 13 (32.5%) cases, 9 (22.5%) were anaplastic astrocytoma, and 2 (5%) cases were diagnosed as pilocytic astrocytoma. Males were slightly more affected than females with a ratio of 1.6:1. Maximum number of cases (25%) were found in the 3rd decade and then in 5th, 6th and 7th decade (17.5%) each. Least number (2.5%) of cases were found in 1st decade of life. Conclusion: Glioblastoma multiforme is the most common astrocytic brain tumour in adults, and pilocytic astrocytoma is the least common brain tumour.

Pak J Physiol 2020;16(3):22–4

Author Biographies

Uzma Shaheen, College of Physicians and Surgeons, Pakistan

Assistant Professor Pathology Department, Dera Ghazi Khan Medical College, Dera Ghazi Khan

Sadia Nazir, Dera Ghazi Khan Medical College, Dera Ghazi Khan, Pakistan

Associate Professor Obstetrics and Gynaecology Department, Dera Ghazi Khan Medical College, Dera Ghazi Khan

Naseem Jahan, Dera Ghazi Khan Medical College, Dera Ghazi Khan, Pakistan

Assistant Professor Physiology Department, Dera Ghazi Khan Medical College, Dera Ghazi Khan

Muhammad Wahid Saleem, Ghazi Khan Medical College, Dera Ghazi Khan, Pakistan

Associate Professor ENT Department, Dera Ghazi Khan Medical College, Dera Ghazi Khan

Zohaib Ashraf, Ghazi Khan Medical College, Dera Ghazi Khan, Pakistan

Demonstrator Pathology Department, Dera Ghazi Khan Medical College, Dera Ghazi Khan

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Published
2020-09-30
How to Cite
1.
Qaisrani A, Shaheen U, Nazir S, Jahan N, Saleem M, Ashraf Z. Morphological analysis of astrocytoma. PJP [Internet]. 30Sep.2020 [cited 17Jan.2021];16(3):22-4. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/1266