Anthropometric variable as a sign for diagnosing insulin resistance

Abstract

Objective: To evaluate the association of the Body mass index (BMI) and Waist hip ration (WHR) with insulin resistance.

Study Design: Cross sectional study.

Place and Duration of Study: King Edward Medical University in collaboration with Mayo Hospital Lahore during November 2016- March 2017. Subjects and Methods: After taking the ethical approval from the institutional ethical committee, 148 subjects enrolled by non-probability convenient technique. Blood samples of each subject were drawn. Anthropometric measures were recorded, basal sugar level and serum insulin levels were analyzed.

Results: 148 subjects of both genders were screened for insulin resistance with mean age, BMI and waist to hip ratio were 44.81 ± 6.20, 31.25 ± 4.26, 0.94 ± .05 respectively. Of total population 70.9% were female subjects and 29.1% were male subjects. Females are at greater risk of developing insulin resistance than males as odd ratio is 0.609 with P-value .003* and is statistically significant. Significant positive association of HOMA-IR was found with BMI (P value 0.016*) however, no association was found with waist to hip ratio (P value 0.08).

Conclusion: Raised body mass index (BMI) is associated with insulin resistance. While waist hip ratio is not associated with insulin resistance.