Prevalence and determinants associated with metabolic syndrome among adults in district Khairpur Mirs Sindh

Abstract

Background: Metabolic Syndrome (MetS) is precursor and diagnostic criteria for Diabetics and Cardiovascular Diseases (CVD). This study investigated the prevalence of MetS and its risk factors among adults of District Khairpur Sindh. Methods: A cross-sectional study was carried out using IDF and NCEP-ATP-III criteria. Demographic and lifestyle data was obtained from participants by interview using Global Physical Activity Questionnaire following WHO guidelines. Besides standard anthropometric measurements and BP, fasting blood glucose and lipid profile were analysed in Research and Diagnostic Laboratory of Microbiology Department, Shah Abdul Latif University, Khairpur. Data was processed on SPSS-22, and presented as Mean±SD and percentages. Unpaired t-test was applied and Odds ratio was calculated, and p?0.05 was taken as significant. Results: A total of 394 healthy adults were randomly contacted; handicapped and non-willing subjects were excluded. Among them, 202 adults, 109 (54%) male and 93 (46%) female agreed to participate. Mean age of subjects was 33.38±12.61 years (male 34.39±12.96, and females 32.19±12.14). The overall prevalence of MetS was 35.6% and 24.3% in males and females respectively. The age group 41?50 was at the highest risk of MetS according to reference values of NCEP-ATP-? (OR: 17.56, p<0.0001) and IDF (OR: 12.53, p<0.0001). BMI and LDL were significantly (p<0.05) higher in female, whereas WHR was significantly higher in male (p<0.05). All other components were statistically non-significant. Conclusion: The prevalence of MetS was found higher using IDF criteria. It increases with age. Women show higher prevalence of MetS than men in older age group.

Pak J Physiol 2019;15(1):59?62