COMPARISON OF VITAMIN D AND LIPID PROFILE BETWEEN RURAL AND URBAN POPULATION

Abstract

Background: The two major sources of vitamin D are food and sunlight. Uncontrolled urbanization leads to undue air pollution which may lead to increased prevalence of hypovitaminosis D among the urban population. This study was designed to compare the levels of serum vitamin D and lipid profile in adequately sun exposed population of rural and urban areas. Methods: This study was conducted on 80 male participants. Group 1 (n=40) comprised of rural residents and group 2 (n=40) of urban residents, all with adequate and equal exposure to sunlight. Serum vitamin D levels were measured using ELISA. Lipid profile was measured using enzymatic colorimetric methods. Results: In rural group, sixteen participants (40%) had sufficient whereas 24 (60%) had insufficient vitamin D. No participant was found to be in deficient category. In urban group one participant (2.5%) was found in deficient and one (2.5%) in sufficient categories whereas 38 (95%) were found to be in insufficient category. The difference in frequency was found to be significant (p<0.001). Median and interquartile range of vitamin D in group 1 and II was 68 (56–54) and 49 (42–56) ?g/ml and the difference was significant (p<0.001). There was no difference between the two groups for triglycerides, total cholesterol and low-density lipoproteins, however, high density lipoproteins were significantly lower in group II as compared to group I (39.5±7.6 vs 47.6±9.0, p<0.001). Conclusion: Urban population had lower levels of vitamin D and high-density lipoproteins as compared to rural population.

Pak J Physiol 2018;14(4):32–5