HEPATIC ENCEPHALOPATHY IN CHRONIC LIVER DISEASE PRODUCED BY CHRONIC VIRAL HEPATITIS

Authors

  • Aamir Nazir Department of Physiology, Ayub Medical College, Abbottabad, Pakistan.
  • Alruba Taimoor Department of Physiology, Ayub Medical College, Abbottabad, Pakistan.
  • Bibi Munazza Department of Physiology, Ayub Medical College, Abbottabad, Pakistan.
  • Sadaf Anwar Qureshi Department of Pathology, Ayub Medical College, Abbottabad, Pakistan.

Abstract

Background: Hepatic encephalopathy (HE) involves neuropsychiatric dysfunction as a result of metabolic disturbance. The objective of the study was to determine and compare grades of hepatic encephalopathy in patients of viral hepatitis B, C, and co-infection. Methods: A cross-sectional study was designed which included seventy five patients of chronic HBV, HCV, and co-infection of either sex, aged 35 years or above. The patients were equally divided into 3 groups. Hepatic encephalopathy was classified into four grades based on the West Haven classification. Results: Out of the 75 subjects, 51 (68.0%) were males and 24 (32.0%) were females. The Mean age was 44.69±7.423 years. Grade I hepatic encephalopathy was a significant feature of both chronic HCV and co-infection groups. The development of grade II encephalopathy was more marked in chronic HBV group, while grade III encephalopathy was more frequent in chronic HCV group. However, frequency distribution of grade IV encephalopathy remained same in all groups. Conclusion: The study concluded that progression of encephalopathy was not more marked in co-infection group. In fact, hepatic encephalopathy equally developed in study groups.

Keywords: Chronic liver disease, Hepatic encephalopathy, viral hepatitis

Pak J Physiol 2017;13(2):38–40

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Author Biography

Aamir Nazir, Department of Physiology, Ayub Medical College, Abbottabad, Pakistan.

Assistant Professor of Physiology, Ayub Medical College, Abbottabad, Pakistan.

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Pak J Physiol 2017;13(2)

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Published

30-06-2017

How to Cite

1.
Nazir A, Taimoor A, Munazza B, Qureshi SA. HEPATIC ENCEPHALOPATHY IN CHRONIC LIVER DISEASE PRODUCED BY CHRONIC VIRAL HEPATITIS. Pak J Phsyiol [Internet]. 2017 Jun. 30 [cited 2024 Apr. 20];13(2):38-40. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/50

Issue

Vol. 13 No. 2 (2017): Pakistan Journal of Physiology

Section

Original Article

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Pakistan Journal of Physiology, Pak J Physiol, PJP is FREE for research and academic purposes. It can be freely downloaded and stored, printed, presented, cited and quoted with full reference of, and acknowledgement to the PJP.