PREVALENCE OF OSTEOPENIA AND OSTEOPOROSIS IN WOMEN USING DUAL ENERGY X-RAY ABSORPTIOMETRY SCAN
Abstract
Objective: To calculate the prevalence of osteopenia and osteoporosis in premenopausal and postmenopausal females of Pakistan by using Dual Energy X- ray Absorptiometry (DXA) Scan for the first time.
Methodology: This cross-sectional study was conducted at Dow University of Health Sciences (DUHS), Karachi. Female subjects aged 25 to 85 years were randomly selected and divided into premenopausal Group I and postmenopausal Group II using proformas filled from patient’s history. Each group was subdivided into normal (pre A, post A), osteopenic (pre B, post B) and osteoporotic (pre C, post C) groups by DXA Scan. Number of females in each subgroup were divided by total number of females in each group and multiplied by hundred to get the point prevalence in percentage for the month of December 2011.
Results: In premenopausal Group I, prevalence of osteopenia and osteoporosis was 12.9 % and 43.5% respectively while 43.5% females were normal. In postmenopausal Group II prevalence of osteopenia was 42.6% and osteoporosis was 29.2% while 28% females came out to be normal.
Conclusion: It was concluded that osteopenia is equally prevalent in females of Pakistan irrespective of menopausal status whereas osteoporosis is found to be more prevalent in postmenopausal females compared to premenopausal females.
References
Ward MM. Estimating disease prevalence and incidence using administrative data: some assembly required. J Rheumatol. 2013;40(8):1241–1243. doi: 10.3899/jrheum.130675
Osteoporosis prevention, diagnosis, and therapy, NIH Consens. Statement 17 (1) (2000) 1–45. Available from: https://scholar.google.com/scholar?q=Osteoporosis+prevention,+diagnosis,+and+therapy,+NIH+Consens.+Statement+17+(1)+(2000)+1%E2%80%9345.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Khan AH, Jafria L, Ahmeda S, Noordinb S. Osteoporosis and its perspective in Pakistan: A review of evidence and issues for addressing fragility fractures. Annals of Medicine and Surgery. 2018; 29:19-25. doi: 10.1016/j.amsu.2018.03.019
Neema, V. Shweta & S. Inamdar. Prevalence of Osteoporosis using Quantitative Ultrasound for Menopausal women in Rural and Urban Area. The Internet Journal of Gynecology and Obstetrics. 2010; 13:1. Available from:http://ispub.com/IJGO/13/1/3688
Vijayakumar R, Bu¨sselberg D. Osteoporosis: An under-recognized public health problem, Journal of Local and Global Health Science. 2016:1. doi: https://doi.org/10.5339/jlghs.2016.2
Ejaz S, Qureshi M.A, Ali M, Prevalence of osteoporosis and osteopenia among Pakistani pre and post menopausal women. Journal of Dental and Medical Sciences. 2012;2(6):12–17. doi: 10.1016/j.amsu.2018.03.019
Ahlborg H G, Rosengren B E1, Järvinen T L N, Rogmark C, Nilsson JA, Sernbo I,et al. Prevalence of Osteoporosis and incidence of hip fracture in women - secular trends over 30 years. BMC Musculoskeletal Disorders. 2010; 11:48. doi: 10.1186/1471-2474-11-48.
Abushaikha L Omran S. A Survey of Osteoporosis Risk Factors and Practices among Jordanian Women. Journal of International Women's Studies 2010; 11(4):153-161. Available at: http://vc.bridgew.edu/jiws/vol11/iss4/11
Narang A, Arora S, Nagpal L. Osteoporosis and Homoeopathic Management. Posted April 2010. Available from: https://researchinhomeopathy.org/osteoporosis-and-its-homoeopathic-management/
F. Cosman, et al., Clinician's guide to prevention and treatment of osteoporosis, Osteoporos. Int. 2014; 25(10):2359–2381. doi: 10.1007/s00198-014-2794-2
Hadji P, Klein S, Gothe H, Haussler B, Kless T, Schmidt T, et al. The epidemiology of osteoporosis –Bone Evaluation Study (BEST): An analysis of routine health insurance data. Deutsches A¨rzteblatt Int. 2013;110(4):52–57. doi: 10.3238/arztebl.2013.0052.
Iki M. Epidemiology of osteoporosis in Japan. Clin Calcium. 2012; 22(6):797–803. Available from: https://pubmed.ncbi.nlm.nih.gov/22653016/
Gheita TA, Hammam N. Epidemiology and awareness of osteoporosis: a viewpoint from the Middle East and North Africa. Int. J. Clin. Rheumatol. 2018; 13(3):134-147. Available From: https://www.openaccessjournals.com/articles/epidemiology-and-awareness-of-osteoporosis-a-viewpoint-from-the-middle-east-and-north-africa.pdf
Zahoor S, Ayub U. Prevalence of osteoporosis in postmenopausal women visiting police and services hospital, Peshawar NWFP. JPMI. 2010; 24(1):4–8. Available from: https://jpmi.org.pk/index.php/jpmi/article/view/1008
Fatima M, Nawaz H, Kassi M, Rehman R, Kasi P M, Kassi M, et al. Determining the risk factors and prevalence of osteoporosis using quantitative ultrasonography in Pakistani adult women, Singap. Med. J. 2009; 50(1):20–28. Available from: http://www.smj.org.sg/sites/default/files/5001/5001a2.pdf
Baig L,. Mansuri F.A, Karim S.A. Association of menopause with osteopenia and osteoporosis: results from population based study done in Karachi. J Coll Physicians Surg Pak. 2009;19(4):240–244. Available from: https://pubmed.ncbi.nlm.nih.gov/19356340/
Lowe, N.M., et al., Dietary calcium intake, vitamin D status, and bone health in postmenopausal women in rural Pakistan. J. Health Popul. Nutr. 2011;29(5):465–470. doi: 10.3329/jhpn.v29i5.8900
Mamji MF, Hasan J, MS Sabri. Risk Factors for Osteoporosis in post-menopausal Women with Hip Fractures. Journal of Surgery Pakistan (International). 2010;15:82-86. Available from:http://old.jsp.org.pk/Issues/JSP%2015%20(2)%20April%20-%20June%202010/Farooq%20Mamjee.pdf
Naeem S.T et al. Bone turnover markers for osteoporosis status assessment at baseline in postmenopausal Pakistani females. J Coll Physicians Surg Pak. 2016; 26(5):408–412. Available from: https://pubmed.ncbi.nlm.nih.gov/27225148/
Jaleel R, F Nasrullah,. Khan AH, Osteopenia in the younger females, Journal of Surgery Pakistan (International). 2010;15(1):29–33. Available from: http://old.jsp.org.pk/Issues/JSP%2015(1)%20Jan%20March%202010/Riffat%20Jalil%20OA.pdf
Lateef M, Baig M, Azhar A. Estimation of serum osteocalcin and telopeptide-C in postmenopausal osteoporotic females. Osteoporos. Int. 2010; 21(5):751–755. doi: 10.1007/s00198-009-1001-3.
Haq IU, Zahid M. Osteoporosis; prevalence among the postmenopausal women. Prof. Med. J. 2009;16:424–427. Available from: https://scholar.google.com/scholar?q=Osteoporosis%3B+prevalence+among+the+postmenopausal+women.+Prof.+Med.+J.+2009%3B16:424%E2%80%93427.+Available+from:&hl=en&as_sdt=0&as_vis=1&oi=scholart
Hafeez F, Zulfiqar S, Hasan S, Khurshid R. An assessment of osteoporosis and low bone density in postmenopausal women. Pak J Physiol. 2009;5(1):41-44. Available from: http://www.pps.org.pk/PJP/5-1/Farida.pdf
Habiba U, Ahmed S, Hassan L. Predisposition to osteoporosis in postmenopausal women, J Coll Physicians Surg Pak. 2002;12:297–301. Available from: https://www.researchgate.net/publication/288634431_Predisposition_to_osteoporosis_in_postmenopausal_women
International Data Base IDB. International Programs Center, Population Division, US Bureau of Census, 2004. Available from: https://www.census.gov/programs-surveys/international-programs/about/idb.html
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