@article{Malik_Dilawar_Qureshi_Khurram_Khan_Malik_2018, title={EFFECT OF IRON WITH MINERAL AND MULTIVITAMIN SUPPLEMENTATION ON TRANSFERRIN SATURATION INDEX IN IRON DEFICIENCY ANEMIA DURING PREGNANCY}, volume={8}, url={https://pjp.pps.org.pk/index.php/PJP/article/view/753}, abstractNote={<p><strong>Background: </strong>Anaemia during pregnancy is associated with labour/delivery complications like, preterm delivery, low birth weight, reduced infant iron stores, impaired mother-child interactions, and increased infant and maternal mortality. The objective of current study was to find out whether supplementation of oral iron (three times a day) would affect Transferrin Saturation Index as effectively as supplementation with combination therapy (iron with multiple vitamin and minerals) in pregnant women with iron deficiency anaemia. <strong>Methods</strong>: Two hundred primigravidae visiting the obstetric outpatient department of Services Hospital Lahore, between 14<sup>th</sup> and 18<sup>th</sup> week of gestation were included in the study. Among 200 pregnant women, 100 women receiving once daily tablet of supplementation including 2 supplements in tablet form containing 60 mg Iron with multivitamin and minerals were considered as group A. Group B consisted of 100 women receiving ferrous sulfate tablet three times a day (60 mg elemental iron). Level of serum iron and Total Iron Binding Capacity (TIBC) were estimated by standard kit methods. After informed consent, blood samples were taken between 14<sup>th</sup> to 18<sup>th</sup> week of gestation and follow-up samples were taken at 36<sup>th</sup> week of gestation. <strong>Results:</strong> Levels of hematological parameters were compared before and after therapy at 14<sup>th</sup> to 18<sup>th</sup> week and 36<sup>th</sup> weeks respectively.  The level of TIBC was increased significantly (<em>p</em><0.001) after the combination therapy. Ratio of iron to TIBC or transferrin saturation index was markedly decreased after the combination therapy in this group. The level of TIBC was significantly decreased (<em>p</em><0.001) after the therapy. Ratio of iron to TIBC or transferrin saturation index was markedly increased after the iron therapy in this group. </p> <p><strong>Conclusion: </strong>Supplementation of iron with multivitamins and minerals has a role in increasing TIBC in pregnant females with iron deficiency anaemia.</p>}, number={1}, journal={Pakistan Journal of Physiology}, author={Malik, Samina and Dilawar, Aalia and Qureshi, Ghazala and Khurram, Usman and Khan, Ramsha and Malik, Samina}, year={2018}, month={May}, pages={19–22} }