@article{Khan_Majeed_Sarwar_2013, title={HEART RATE VARIABILITY: COMPARISON OF 24 HOURS WITH 72 HOURS HOLTER MONITORING IN HEALTHY ADULTS}, volume={9}, url={https://pjp.pps.org.pk/index.php/PJP/article/view/385}, abstractNote={<p><strong>Background:</strong> Heart rate variability represents oscillations in intervals between heart beats that is characterised as variable RR intervals on standard ECG. It provides information about autonomic as well as non-autonomic regulatory mechanisms in health and disease states. Reduced heart rate variability is considered a non-invasive marker of autonomic dysfunction that can predict wide range of cardio-pulmonary disorders leading to sudden cardiac death. The objective of this study was to compare heart rate variability recorded from 24 hours with that recorded from 72 hours of holter monitoring in healthy adults. <strong>Methods: </strong>Thirty-seven healthy voluntary adults were selected and holter monitored for 72 hours using Reynolds medical holter monitors ‘life card CF’. Statistical time domain parameters, i.e., SDNN, SDANN and RMSSD were calculated from 24 hours and 72 hours ambulatory ECG recordings. The data were analysed using SPSS-21. Paired sample <em>t</em>-test was used to compare the mean values of heart rate variability parameters. <strong>Results: </strong>Mean values of SDNN, SDANN and RMSSD from 24 hours holter monitoring were 141.62 ms, 125.16 ms, and 28.40 ms and those recorded from 72 hours of holter monitoring were 136.94 ms, 122.37 ms, and 26.46 ms respectively. Differences between none of the variables from the two recordings were statistically significant (<em>p</em>>0.05) <strong>Conclusion: </strong>Increase in duration of holter monitoring has no advantage on time domain parameters of heart rate variability in healthy individuals.</p> <p><strong>Pak J Physiol 2013;9(2):26–8</strong></p>}, number={2}, journal={Pakistan Journal of Physiology}, author={Khan, Muhammad Alamgir and Majeed, Syed Muhammad Imran and Sarwar, Madiha}, year={2013}, month={Dec.}, pages={26–28} }