INFLUENCE OF HYPERTENSION AND DIABETES MELLITUS ON SENILE CATARACT

Abstract

The aim of this study was to evaluate the influence of modifiable risk factors like hypertension and diabetes on senile cataract. Methods: This study was conducted in the Department of Physiology, Basic Medical sciences Institute, Jinnah Postgraduate Medical Centre (JPMC) in collaboration with Ophthalmology Department of JPMC and Physiology Department at Dow Medical College Karachi. After selection of the subjects by consecutive sampling, a proforma was filled. A complete eye examination was performed and the subjects were asked to attend the laboratory after 12 hour fasting. Samples were collected, sera were stored for analysis. Blood pressure was measured by mercury sphygmomanometer. Subjects were divided into 4 groups Normotensive, Normoglycaemic with Cataract as Control (Group-A), Hypertensive with Cataract (Group-B), Diabetics with Cataract (Group-C) and Hypertensive and Diabetics with Cataract (Group-D). Results: This study revealed that the Diabetes Mellitus and Hypertension are modifiable risk factors that influence positively on the development of senile cataract. Conclusion: Senile cataract is positively influenced by Diabetes Mellitus and Hypertension.