EARLY DETECTION OF CARDIAC FAILURE IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS

Authors

  • Mevo Khan Zardari Department of Physiology, People’s Medical College for Girls, Nawabshah, Sindh, Pakistan
  • Sikander Adil Mughal Department of Physiology, People’s Medical College for Girls, Nawabshah
  • Safdar Ali Shaikh Department of Physiology, Chandka Medical College, Larkana
  • Muhammad Azhar Mughal Department of Pharmacology, Sindh Medical College, Dow University of Health Sciences, Karachi
  • Muhammad Azhar Mughal Department of Pharmacology, Sindh Medical College, Dow University of Health Sciences, Karachi
  • Syed Tousif Ahmed Department of Physiology, Ziauddin Medical College, Ziauddin University, Clifton Karachi

Keywords:

Chronic Obstructive Pulmonary Diseases, Valsalva manoeuvre, Cardiac Failure, Spirometry

Abstract

During the past 20 years the incidence of Chronic Obstructive Pulmonary Disease (COPD) has increased considerably. In most patients with severe COPD if they live long enough corpulmonale eventually developed. The present study was designed for detection of cardiac failure in COPD subjects by Valsalva manoeuvre, i.e., Valsalva ratio, may offer the best chance to check and decrease the rising trend of mortality due to COPD. Methods: A total of 120 male subjects were included during the course of present study. The patients suffering from COPD were selected from the Medical Department and Chest Medicine of Jinnah Postgraduate Medical Centre Karachi. The patients were selected on the basis of history and clinical examination and confirmed by x-ray chest and pulmonary function by Spirometry. Results: The mean value for the age subgroups B and C of control were significant when compared with age sub groups B and C of COPD subjects without cardiac failure except sub age group A. The mean values for all the three age subgroups of control were highly significant (p<0.001) when compared with the mean value of corresponding age subgroups of COPD subjects with cardiac failure. This study revealed that the Valsalva ratio in the control subject of all age groups and COPD without cardiac failure in young age subgroups was above 1.5 and slightly decreased with increasing age. All the COPD with cardiac failure subjects showed an abnormal Valsalva ratio. 

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Published

31-12-2008

How to Cite

1.
Zardari MK, Mughal SA, Shaikh SA, Mughal MA, Mughal MA, Ahmed ST. EARLY DETECTION OF CARDIAC FAILURE IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS. Pak J Phsyiol [Internet]. 2008 Dec. 31 [cited 2024 Mar. 29];4(2):17-9. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/666