AN EARLY DIAGNOSIS OF FOETAL DISTRESS BY ESTIMATING THE MATERNAL BLOOD GAS LEVELS DURING INTRAPARTUM PERIOD

Authors

  • Nusrat Zareen Assistant Professor, Department of Physiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan
  • Rukhsana Rubeen Department of Biochemistry, Dow International Medical College, DUHS, Karachi
  • Muhammad Saleem Khanzada *Dow Diagnostic Reference and Research Laboratory, Ojha, DUHS, Karachi
  • Zakir Jalal Khanzada University of North Dakota, USA. Department of Gynaecology and Obstetrics, Liaquat Medical University Hospital, Sindh.
  • Zakia Zaheen Department of Gynaecology and Obstetrics, Liaquat Medical University Hospital, Sindh
  • Syed Touseef Ahmed Department of Physiology, Ziauddin Medical University, Karachi.

Keywords:

Maternal asphyxia, Intrapartal asphyxia, Lactic acidemia

Abstract

The purpose of this study was to find out the affect of maternal asphyxia influencing the foetus by comparison of the maternal arterial blood gas (ABGs) and acid base levels of normal full term females with the ABGs and acid base values of term females showing any subjective signs of foetal asphyxia during intrapartum period. Methods: In this case control study maternal ABGs and acid base levels of 40 normal term pregnant ladies were compared with 40 other term pregnant females with subjective signs of foetal asphyxia (i.e., foetal heart rate >160 bpm or <120 bpm, meconium staining liquor during intrapartum period or Apgar score <5 at one minute after delivery to confirm the foetal distress. Lactic acid and pH were also estimated to assess the acid base balance. Result: There was considerable difference of lactic acid (LA) and Pco2 levels which were significantly increased (p<0.025) in asphyxiated mothers (AM) as compared with control mothers (CM). No significant difference was observed regarding pH values, bicarbonate ions (HCO3 -), base excess (BE), carbon dioxide content (CO2ct) and percentage saturation of oxygen (%O2SAT) levels in both CM and AM groups. The levels of haemoglobin (Hb), packed cell volume (PCV), partial pressure of oxygen (PO2) and oxygen content (O2ct ) in AM group were found significantly lower (p<0.0001) as compared to CM group. 

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Published

30-06-2009

How to Cite

1.
Zareen N, Rubeen R, Khanzada MS, Khanzada ZJ, Zaheen Z, Ahmed ST. AN EARLY DIAGNOSIS OF FOETAL DISTRESS BY ESTIMATING THE MATERNAL BLOOD GAS LEVELS DURING INTRAPARTUM PERIOD. Pak J Phsyiol [Internet]. 2009 Jun. 30 [cited 2024 Apr. 25];4(1):13-6. Available from: https://pjp.pps.org.pk/index.php/PJP/article/view/641